Case report GVHD dry eyes treated with autologous serum tears
نویسندگان
چکیده
Two cases of GVHD with severe dry eyes are reported where conventional therapy failed to control ocular signs and symptoms. Autologous serum tears, however, resulted in a beneficial clinical effect with marked attenuation of the symptoms. This therapy proved to be safe during 10 months of treatment. Bone Marrow Transplantation (2000) 25, 1101–1103.
منابع مشابه
Ocular manifestations of graft-versus-host disease: 10 years’ experience
PURPOSE To evaluate the ocular presentation, treatment, and clinical course of graft-versus-host disease (GVHD). DESIGN Retrospective case series. PARTICIPANTS Two hundred and forty-nine patients with systemic GVHD were included in the study. METHODS Ocular and systemic data were collected from 2003 to 2013. MAIN OUTCOME MEASURES Mortality, visual acuity, and response of ocular symptoms...
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Purpose. Report a case of limbitis secondary to autologous serum eye drops in a patient with atopic keratoconjunctivitis. Design. Interventional case report. Methods. A 32-year-old African American female with atopic keratoconjunctivitis (AKC) presented with chronic dry eye and diffuse punctate epithelial erosions refractory to conservative treatment. She was initially managed with cyclosporine...
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AIM To evaluate in vivo changes after therapy using autologous serum (AS) eye drops in Sjögren's syndrome (SS)-related dry eyes by confocal microscopy. PATIENTS AND METHODS In this study, 24 patients with SS-related dry eyes [12 in AS eye drop therapy and 12 in artificial tear (AT) therapy] and 24 healthy volunteers were recruited. Ocular Surface Disease Index (OSDI), central corneal thicknes...
متن کاملThe use of autologous serum for the treatment of ocular surface disease at a Swedish tertiary referral center
PURPOSE The study aims to describe an intact cohort with mixed ocular surface disease (OSD) treated with autologous serum (AS) eye drops in a tertiary eye center. PATIENTS AND METHODS All cases (n=32 eyes, 24 patients) treated with AS for OSD at the Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, between 2002 and 2013 were included and medical records were reviewed retr...
متن کامل[Autologous serum-eye-drops for ocular surface disorders. A literature review and recommendations for their application].
The natural tear film has mechanical, optical, antimicrobial and nutritional properties. Tear film components, such as EGF, fibronectin and vitamin A, play a vital role in the proliferation, migration and differentiation of the corneal and conjunctival epithelium. In ocular surface disease, such as severe dry eye, the epithelia may be depleted of these nutritional factors. Replacing the aqueous...
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تاریخ انتشار 2000